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<!-- Creation Date :2023-11-07T13:30:23.5933+00:00 -->
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  <xsd:element id="snse_ShareRepurchaseLiabilityRecordedAtContractualValueNetOfIssuanceCost" name="ShareRepurchaseLiabilityRecordedAtContractualValueNetOfIssuanceCost" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="snse_FairValueLiabilitiesLevelOneToLevelTwoTransfersAmount" name="FairValueLiabilitiesLevelOneToLevelTwoTransfersAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_GainOnSaleOfEquipment" name="GainOnSaleOfEquipment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="snse_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsGranted" name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsGranted" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_NumberOfFormerOfficers" name="NumberOfFormerOfficers" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployeeStockPurchasePlanExpense" name="AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationEmployeeStockPurchasePlanExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="snse_ProceedsFromDisposalsOfPropertyPlantAndEquipmentIncludedInOtherAssets" name="ProceedsFromDisposalsOfPropertyPlantAndEquipmentIncludedInOtherAssets" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsExpired" name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsExpired" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_CommercialPaperAndUSGovernmentAgenciesMember" name="CommercialPaperAndUSGovernmentAgenciesMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="snse_AvailableForSaleSecuritiesContractualMaturityTerm" name="AvailableForSaleSecuritiesContractualMaturityTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_WeightedAverageRemainingLeaseTermAbstract" name="WeightedAverageRemainingLeaseTermAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="snse_UnauditedInterimFinancialInformationPolicyTextBlock" name="UnauditedInterimFinancialInformationPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_OperatingCashFlowsForOperatingSubleases" name="OperatingCashFlowsForOperatingSubleases" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_MarketableSecurityMember" name="MarketableSecurityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="snse_EmployeeStockPurchasePlanExpense" name="EmployeeStockPurchasePlanExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_FairValueLiabilitiesLevelTwoToLevelOneTransfersAmount" name="FairValueLiabilitiesLevelTwoToLevelOneTransfersAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_CambrianPurchaseAgreementMember" name="CambrianPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="snse_DefinedContributionPlanAccruedExpenses" name="DefinedContributionPlanAccruedExpenses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit"/>
  <xsd:element id="snse_PurchaseAgreementNetOfIssuanceCostsAndExciseTaxShares" name="PurchaseAgreementNetOfIssuanceCostsAndExciseTaxShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
  <xsd:element id="snse_ClassOfWarrantOrRightOutstandingAndExercisableAggregateIntrinsicValue" name="ClassOfWarrantOrRightOutstandingAndExercisableAggregateIntrinsicValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_StockIssuedDuringPeriodValueIssuanceOfEquityInExchangeForCompensation" name="StockIssuedDuringPeriodValueIssuanceOfEquityInExchangeForCompensation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_CashCashEquivalentsAndMarketableSecurities" name="CashCashEquivalentsAndMarketableSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit"/>
  <xsd:element id="snse_ResearchEquipmentMember" name="ResearchEquipmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true"/>
  <xsd:element id="snse_LeaseExpirationYear" name="LeaseExpirationYear" type="xbrli:gYearItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false"/>
</xsd:schema>
